I’ve watched a great deal of animation over the course of my lifetime. This is one of the most memorable scenes from the latter half of my life:
Ultimately, I think what gets–and has stuck with–me over the years is the incredible straddling of happiness-joy-carelessness and madness-rage-idiocy. Repetition of elements is key here, I think. The audio helps with this straddling effect, of course, but I think even when the sound is off the mania of that state comes through.